The cardiovascular system in the human body has evolved to support function in the Earth’s gravity environment involving bipedal stance and ambulation. Given that blood and body fluids are drawn downward during standing, autonomic, endocrine, and vascular responses are critical to returning blood from the lower body to the heart and perfuse the brain. Many of these functions are not required during spaceflight, and, in combination with altered blood flow and pressures, results in cardiovascular deconditioning. When not opposed by countermeasures performed during spaceflight to simulate physical work or gravity on Earth, cardiovascular deconditioning can result in low blood volume, cardiac atrophy, vascular dysfunction, orthostatic intolerance, and reduced work capacity, affecting an astronaut’s ability to perform work during and immediately after spaceflight.


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    Title :

    Cardiovascular Deconditioning and Exercise



    Published in:

    Handbook of Bioastronautics ; Chapter : 20 ; 129-153


    Publication date :

    2021-08-17


    Size :

    25 pages




    Type of media :

    Article/Chapter (Book)


    Type of material :

    Electronic Resource


    Language :

    English




    Cardiovascular Deconditioning

    Charles, John B. / Fritsch-Yelle, Janice M. / Whitson, Peggy A. et al. | NTRS | 1999


    Cardiovascular Deconditioning

    J. B. Charles / J. M. Fritsch-Yelle / P. A. Whitson et al. | NTIS | 1999


    Cardiovascular Dynamics during Space Sickness and Deconditioning

    A. L. Goldberger / D. R. Rigney | NTIS | 1991