Advanced multirotor vertical flight aircraft concepts are emerging faster than rigorous individualized tests can investigate their utility and performance. There are several analysis tools that predict multirotor performance and flow characteristics, but the accuracy of these predictions is still being debated due to lack of experimental data from multirotor tests that are needed to validate the analyses. The objective of this paper is to simulate multirotor configurations using two different mid-fidelity rotorcraft analysis tools, Comprehensive Hierarchical Aeromechanics Rotorcraft Model (CHARM) and Rotorcraft Computational Fluid Dynamics (RotCFD), and compare the simulation results to experimental data from a wind tunnel test of the Multirotor Test Bed (MTB). The MTB, developed by NASA Ames Research Center, is a new capability for testing a wide array of advanced vertical take-off and landing (VTOL) rotor configurations, with a primary focus on testing in the U.S. Army 7-by 10-Foot Wind Tunnel at NASA Ames Research Center. The MTB was designed to allow adjustment of the vertical, lateral, and longitudinal placement of up to six rotors, as well as allow tilt adjustment of each rotor and pitch adjustment of the whole assembly. The six-axis load cells under each rotor give the MTB the capability of measuring the rotor performance in a wide array of configurations. The overall goal of the MTB project is to help gain a better understanding of the performance, control, interactional aerodynamics, and acoustics of multirotor and tilting-rotor systems. For the work presented here, the MTB data were used to validate RotCFD and CHARM results for several multirotor test configurations. With confidence in both analyses established by the validation exercise, additional simulations were performed to explore quadrotor configurations that will be tested during the MTB’s second wind tunnel entry planned for 2022. This second tunnel entry will examine quadrotor configurations that represent published NASA reference designs for urban air mobility concept vehicles. Results from this paper confirm the ability of RotCFD and CHARM to simulate multirotor aerodynamic interactions on individual rotor performance under edgewise forward-flight conditions.