BioLEAD: BioLogical Exploration via Autonomous Detection – Using Dielectric Spectroscopy to Monitor Biological Changes in Response to Deep Space Radiation

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BioLEAD: BioLogical Exploration via Autonomous Detection – Using Dielectric Spectroscopy to Monitor Biological Changes in Response to Deep Space Radiation

Elizabeth Hawkins / Ada Kanapskyte / Lauren Liddell / Michael Padgen / Shilpa Bhardwaj / Diana Gentry / Sharmila Bhattacharya / Sergio R. Santa Maria

Abstract

Leveraging the bio-fluidic hardware developed for BioSentinel, we propose a new payload for autonomous missions: BioLEAD – BioLogical Exploration via Autonomous Detection. With NASA's renewed focus to continue human exploration of the Moon (Artemis Program), the BioLEAD payload aims to investigate the effects of the lunar environment on biology, whether onboard a lunar lander, the Lunar Gateway, or as a free-flying CubeSat orbiting the Moon. In place of an optical detection system, BioLEAD will employ a miniaturized, non-invasive dielectric spectroscopy sensor to enable real-time monitoring of biological activity. The sensor operates by relating capacitance measurements to the dielectric properties of the cell, such as cell morphology, doubling time, and cell cycle stage. The implementation of this new sensor technology will address limitations of the optical measurement system used on BioSentinel. It will also advance the use of autonomous bioanalytical microsystems and reveal new information regarding biological responses to the Moon’s radiation environment. Most importantly, BioLEAD’s technology will be adaptable for a wide array of future missions.

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Document information

Title :

BioLEAD: BioLogical Exploration via Autonomous Detection – Using Dielectric Spectroscopy to Monitor Biological Changes in Response to Deep Space Radiation

Contributors:

Elizabeth Hawkins (author) / Ada Kanapskyte (author) / Lauren Liddell (author) / Michael Padgen (author) / Shilpa Bhardwaj (author) / Diana Gentry (author) / Sharmila Bhattacharya (author) / Sergio R. Santa Maria (author)

Conference:

ASGSR 2020 ; 2020 ; Virtual, US

Type of media :

Miscellaneous

Type of material :

No indication

Language :

English

Keywords :

Life Sciences (General) , Biosensor , Dielectric Spectroscopy , Space Radiation