The present disclosure relates to methods and compositions for treating cancer with a diaryl macrocycle in combination with an inhibitor of MAPK/ERK kinase-1 and -2 (MEK1 and MEK2; MAP2K1 and MAP2K2), such as trametinib.


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    Title :

    COMBINATION THERAPY INVOLVING DIARYL MACROCYCLIC COMPOUNDS


    Additional title:

    KOMBINATIONSTHERAPIE MIT DIARYLMAKROCYCLISCHEN VERBINDUNGEN
    POLYTHÉRAPIE IMPLIQUANT DES COMPOSÉS MACROCYCLIQUES DE DIARYLE


    Contributors:
    DENG WEI (author) / ZHAI DAYONG (author) / RODON LAURA (author) / MURRAY BRION W (author) / CUI JINGRONG J (author) / LEE NATHAN V (author)

    Publication date :

    2024-02-14


    Type of media :

    Patent


    Type of material :

    Electronic Resource


    Language :

    English


    Classification :

    IPC:    A61K Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke , PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES / A61P SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS , Spezifische therapeutische Aktivität von chemischen Verbindungen oder medizinischen Zubereitungen / B60H ARRANGEMENTS OR ADAPTATIONS OF HEATING, COOLING, VENTILATING, OR OTHER AIR-TREATING DEVICES SPECIALLY FOR PASSENGER OR GOODS SPACES OF VEHICLES , Anordnung oder Einbau der Heizung, Kühlung, Lüftung oder anderer Luftbehandlungsvorrichtungen für die Fahrzeugräume für Reisende oder Fracht / F24F Klimatisierung , AIR-CONDITIONING / F25B Kältemaschinen, Kälteanlagen oder Kälteverfahren , REFRIGERATION MACHINES, PLANTS, OR SYSTEMS



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