The invention particularly relates to a vehicle rear sub-frame and belongs to the technical field of vehicle manufacturing. The vehicle rear sub-frame comprises a front horizontal pipe, a rear horizontal pipe, a left longitudinal pipe and a right longitudinal pipe which form a #-shaped structure, wherein the left longitudinal pipe and the right longitudinal pipe are respectively connected with the front horizontal pipe and the rear horizontal pipe; an inner connecting plate and an outer connecting pipe are respectively arranged at the places where the two ends of the front horizontal pipe are connected with the left longitudinal pipe and the right longitudinal pipe; an upper control arm left mounting bracket and an upper control arm right mounting bracket are respectively arranged on the middle parts of the left longitudinal pipe and the right longitudinal pipe; a stabilizing rod left mounting bracket and a stabilizing rod right mounting bracket are arranged on the upper parts of the left longitudinal pipe and the right longitudinal pipe; a No. II swing arm left mounting bracket and a No. II swing arm right mounting bracket are arranged on the middle part of the rear horizontal pipe; a No. I swing arm left mounting bracket and a No. I swing arm right mounting bracket are respectively arranged on the end parts of the two ends of the front horizontal pipe; the cross sections of the pipe body sections of the rear horizontal pipe, the left longitudinal pipe and the right longitudinal pipe are consistent; the cross sections of the two ends of the rear horizontal pipe are U-shaped after the two ends of the rear horizontal pipe are pressed and bonded; reinforcing plates are arranged at the two ends of the rear horizontal pipe. The vehicle rear sub-frame is simple in molding process, reasonable in overall structure and high in safety, and the fatigue resistance is enhanced.