Flux Assays in High Throughput Screening of Ion Channels in Drug Discovery
Measuring Drug Action in the Cellular Context Using Protein-Fragment Complementation Assays
Steroid Hormone Receptors and Drug Discovery: Therapeutic Opportunities and Assay Designs
Inhibitor Focusing: Direct Selection of Drug Targets from Proteomes Using Activity-Based Probes
High Throughput Ion-Channel Pharmacology: Planar-Array-Based Voltage Clamp
An Interview with Francis S. Collins, M.D., Ph.D. Director, National Human Genome Research Institute
In Vitro Evolution of Proteins for Drug Development
Recombinant Baculoviruses Used to Study Estrogen Receptor Function in Human Osteosarcoma Cells
Biophysical Methods for Monitoring Cell-Substrate Interactions in Drug Discovery
24-Well Plate Spectrophotometric Assay for Preliminary Screening of Metabolic Activity
An Interview with Maria L. Garcia, Ph.D.
Models of Anergy in the Human Jurkat T Cell Line
A Simple Kinetic Method for Rapid Mechanistic Analysis of Reversible Enzyme Inhibitors
A "Mix and Read" Assay for Insulin Using Fluorometric Microvolume Assay Technology
Driving Affinity Selection by Centrifugal Force
An Interview with D. Lansing Taylor, Ph.D. Chief Executive Officer, Cellomics, Inc.
Automated Electrophysiology: High Throughput of Art
Privileged Structure-Based Combinatorial Libraries Targeting G Protein-Coupled Receptors
Drug Targets in the Voltage-Gated Calcium Channel Family: Why Some Are and Some Are Not
An Interview with Tim Harris, Ph.D.
Characterization of Fatty Acid Synthase Activity Using Scintillation Proximity
A Mechanism-Based In Vitro Anticancer Drug Screening Approach for Phenolic Phytochemicals
Advances in High Content Screening for Drug Discovery
An Encoded Particle Array Tool for Multiplex Bioassays
Coactivators in Assay Design for Nuclear Hormone Receptor Drug Discovery
A One-Arm Homologous Recombination Approach for Developing Nuclear Receptor Assays in Somatic Cells
An Interview with Ronald M. Evans, Ph.D. Investigator, The Salk Institute for Biological Studies