In March 2017, a vertical drop test of a forward fuselage section of a Fokker F-28 MK4000 aircraft was conducted as part of a joint NASA/FAA project to investigate the performance of transport aircraft under realistic crash conditions. In June 2017, a vertical drop test was conducted of a wing-box fuselage section of the same aircraft. Both sections were configured with two rows of aircraft seats, in a triple-double configuration. A total of ten Anthropomorphic Test Devices (ATDs) were secured in seats using standard lap belt restraints. The forward fuselage section was also configured with luggage in the cargo hold. Both sections were outfitted with two hat racks, each with added ballast mass. The drop tests were performed at the Landing and Impact Research facility located at NASA Langley Research Center in Hampton, Virginia. The measured impact velocity for the forward fuselage section was 346.8-in/s onto soil. The wing-box section was dropped with a downward facing pitch angle onto a sloping soil surface in order to create an induced forward acceleration in the airframe. The vertical impact velocity of the wing-box section was 349.2-in/s. A second objective of this project was to assess the capabilities of finite element simulations to predict the test responses. Finite element models of both fuselage sections were developed for execution in LS-DYNA(Registered Trademark), a commercial explicit nonlinear transient dynamic code. The models contained accurate representations of the airframe structure, the hat racks and hat rack masses, the floor and seat tracks, the luggage in the cargo hold for the forward section, and the detailed under-floor structure in the wing-box section. Initially, concentrated masses were used to represent the inertial properties of the seats, restraints, and ATD occupants. However, later simulations were performed that included finite element representations of the seats, restraints, and ATD occupants. These models were developed to more accurately replicate the seat loading of the floor and to enable prediction of occupant impact responses. Models were executed to generate analytical predictions of airframe responses, which were compared with test data to validate the model. Comparisons of predicted and experimental structural deformation and failures were made. Finally, predicted and experimental soil deformation and crater depths were also compared for both drop test configurations.