Update of the Bisphosphonate ISS Flight Experiment
Update of the Bisphosphonate ISS Flight Experiment
- Neue Suche nach: LeBlanc, Adrian
- Neue Suche nach: Matsumoto, Toshio
- Neue Suche nach: Jones, Jeffrey
- Neue Suche nach: Shapiro, Jay
- Neue Suche nach: Lang, Thomas
- Neue Suche nach: Shackelford, Linda
- Neue Suche nach: Smith, Scott M.
- Neue Suche nach: Evans, Harlan
- Neue Suche nach: Spector, Elisabeth
- Neue Suche nach: Ploutz-Snyder, Robert
- Neue Suche nach: Sibonga, Jean
- Neue Suche nach: Keyak, Joyce
- Neue Suche nach: Nakamura, Toshitaka
- Neue Suche nach: Kohri, Kenjiro
- Neue Suche nach: Ohshima, Hiroshi
- Neue Suche nach: Moralez, Gilbert
- Neue Suche nach: LeBlanc, Adrian
- Neue Suche nach: Matsumoto, Toshio
- Neue Suche nach: Jones, Jeffrey
- Neue Suche nach: Shapiro, Jay
- Neue Suche nach: Lang, Thomas
- Neue Suche nach: Shackelford, Linda
- Neue Suche nach: Smith, Scott M.
- Neue Suche nach: Evans, Harlan
- Neue Suche nach: Spector, Elisabeth
- Neue Suche nach: Ploutz-Snyder, Robert
- Neue Suche nach: Sibonga, Jean
- Neue Suche nach: Keyak, Joyce
- Neue Suche nach: Nakamura, Toshitaka
- Neue Suche nach: Kohri, Kenjiro
- Neue Suche nach: Ohshima, Hiroshi
- Neue Suche nach: Moralez, Gilbert
The bisphosphonate study is an international collaboration between the NASA and JAXA space agencies to investigate the potential value of antiresorptive drugs to mitigate the well-established bone changes associated with long-duration spaceflight. Our hypothesis is that an antiresorptive drug in combination with in-flight exercise will ameliorate bone loss and hypercalcuria during long-duration spaceflight. We have completed data analysis for 7 crewmembers treated with alendronate during flight and 3 of 10 controls without treatment. We previously reported the pre/postflight changes in bone density and the pre versus in-flight changes in various biomarkers in crewmembers taking alendronate during flight. The purpose of this report is to compare these results with the 12- month follow-up data. The table below presents these data as a percentage change from baseline either immediately postflight or in-flight (biochemical markers) with a 1-year follow-up.
Dokumentinformationen
Update of the Bisphosphonate ISS Flight Experiment
NASA Human Research Program Investigators'' Workshop ; 2014 ; Galveston, TX, United States
2014-02-10
Aufsatz (Konferenz)
Keine Angabe
Englisch
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